JOURNAL OF UROLOGY AND ANDROLOGY RESEARCH
Original Article
Jun 25, 2026 2 1

Autograft, but with What? Contemporary Practice of Incision/Excision and Autografting in Peyronie’s Disease Treatment

Yernur Ainayev 1 * ,
Ulanbek Zhanbyrbekuly 2,
Nurlan Kissamedenov 2,
Zhalgas Kissameden 2,
Alexey Suchshenko 2,
Bela Zhambulova 1 *
1 Kazakh-Russian Medical University (KRMU), Almaty, Kazakhstan2 Astana Medical University JSC, Astana, Kazakhstan* Corresponding Author
Journal of Urology and Andrology Research, 1(1), 2026, juar001
Publication date: Jun 25, 2026
Full Text (PDF)

ABSTRACT

Introduction: Peyronie's disease (PD) is characterized by the development of fibrous plaques within the tunica albuginea, leading to penile deformity and significant psychological distress. While various surgical options exist, plaque incision or excision with grafting remains the gold standard for correcting complex or severe curvatures (>60–70°). This review evaluates the clinical outcomes, technical success, and complication rates of various autograft materials.
Historically, dermal grafts were the first autografts used but have fallen out of favor due to high rates of penile shortening (45–70%) and de novo ED (up to 66.7%). Saphenous vein grafts (SVG) demonstrate an initial success rate of ~85.6%, though long-term follow-up indicates a decline in straightness and rising ED rates (22.5%). Tunica albuginea and tunica vaginalis grafts show high technical success (90–100%) with low metabolic demand. More contemporary options, specifically fascia (lata and temporalis) and buccal mucosa grafts (BMG), show superior outcomes. Fascia grafts report technical success rates near 100% with minimal shortening. BMG demonstrates a 94.1% success rate with low de novo ED (0–10%) and rapid tissue integration.

KEYWORDS

Peyronie's Disease Autografts Corporoplasty Penile Plaque Erectile Dysfunction

CITATION (Vancouver)

Ainayev Y, Zhanbyrbekuly U, Kissamedenov N, Kissameden Z, Suchshenko A, Zhambulova B. Autograft, but with What? Contemporary Practice of Incision/Excision and Autografting in Peyronie’s Disease Treatment. Journal of Urology and Andrology Research. 2026;1(1):juar001.
APA
Ainayev, Y., Zhanbyrbekuly, U., Kissamedenov, N., Kissameden, Z., Suchshenko, A., & Zhambulova, B. (2026). Autograft, but with What? Contemporary Practice of Incision/Excision and Autografting in Peyronie’s Disease Treatment. Journal of Urology and Andrology Research, 1(1), juar001.
Harvard
Ainayev, Y., Zhanbyrbekuly, U., Kissamedenov, N., Kissameden, Z., Suchshenko, A., and Zhambulova, B. (2026). Autograft, but with What? Contemporary Practice of Incision/Excision and Autografting in Peyronie’s Disease Treatment. Journal of Urology and Andrology Research, 1(1), juar001.
AMA
Ainayev Y, Zhanbyrbekuly U, Kissamedenov N, Kissameden Z, Suchshenko A, Zhambulova B. Autograft, but with What? Contemporary Practice of Incision/Excision and Autografting in Peyronie’s Disease Treatment. Journal of Urology and Andrology Research. 2026;1(1), juar001.
Chicago
Ainayev, Yernur, Ulanbek Zhanbyrbekuly, Nurlan Kissamedenov, Zhalgas Kissameden, Alexey Suchshenko, and Bela Zhambulova. "Autograft, but with What? Contemporary Practice of Incision/Excision and Autografting in Peyronie’s Disease Treatment". Journal of Urology and Andrology Research 2026 1 no. 1 (2026): juar001.
MLA
Ainayev, Yernur et al. "Autograft, but with What? Contemporary Practice of Incision/Excision and Autografting in Peyronie’s Disease Treatment". Journal of Urology and Andrology Research, vol. 1, no. 1, 2026, juar001.

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